Concerning Developer Studio 2.3.2, we reproduced the problem and we have a workaround.
Actually, the integrated version of Eclipse simply doesn’t know anything about Windows 10 and Java 8 as it is too old. But it’s not possible to install any other Java version on Windows 10.
The root cause of the problem is that DS is not able to resolve the path to the native DLLs it needs to access to the serial ports.
Create a folder named dlls in Developer Studio folder (e.g. C:\Program Files (x86)\Sierra Wireless\Developer Studio\dlls)
In this folder, copy the 2 rxtx*.dll files you can find in \plugins\gnu.io.rxtx.win32.x86_2.1.7.v2013XXXXXXXX\os\win32\x86
Open the \plugins\com.swi.tm.core.win32_184.108.40.206310241534.jar with an archive manager program (e.g. 7-zip), and extract the libUSBNotifier.dll file to this folder as well
Edit the \m2mstudio.ini file, and add the -Djava.library.path=C:\Program Files (x86)\Sierra Wireless\Developer Studio\dlls argument at the end of the file, on a new separated line
You can then start DS, and the serial ports should be displayed again.
(4) Copy rxtxParallel.dll and rxtxSerial.dll from plugins\gnu.io.rxtx.win32.x86_220.127.116.11311191600\os\win32\x86 to dlls\
There is no folder gnu.io.rxtx.win32.x86_18.104.22.168311191600 when you install Developer Studio 2.3.2.
You need to install Developer Studio 2.3.2, then install Developer Studio 3.5.
You can retrieve gnu.io.rxtx.win32.x86_22.214.171.124311191600 from the directory where DS3.5 is installed.
And following the given procedure.